CORDIS Project
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This research explores the role of the RANK signaling pathway in breast cancer development, aiming to provide insights into prevention strategies. It leverages data from large cohort studies to investigate pre-diagnosis factors associated with breast cancer risk.
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer mortality in women worldwide.
The recently identified Receptor Activator of Nuclear Factor (NF)-κB (RANK)-axis has stimulated novel research in the field of breast cancer etiology, treatment, and prevention.
Experimental data implicate RANK signalling in mammary tumor development.
Preliminary human data show increased RANK expression correlated with poor outcome, and circulating concentrations of osteoprotegeri…
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
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