CORDIS Project
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This project investigates the role of Rac GTPase signaling in intestinal stem cells, focusing on how it regulates their behavior during normal and pathological conditions. By understanding these molecular mechanisms, the research aims to inform new strategies for cancer treatment and improve intestinal health.
Diseases that affect the digestive system are the most common causes of mortality.The intestinal epithelium is a highly proliferative tissue, where most cells are replaced on a weekly basis.
Intestinal stem cells (ISCs) are crucial for tissue maintenance and regeneration after wounding.
Homeostasis within the stem cell compartment is controlled by extrinsic and intrinsic signals.
The intrinsic cellular machinery that coordinates stem cell division, expansion and final differentiation is poorly u…
KOBENHAVNS UNIVERSITET
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