CORDIS Project
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This project aims to develop a practical method for synthesizing enantiopure α-arylated quaternary amino acids, which are valuable in pharmaceuticals and agrochemicals. The method is designed to be cost-effective and environmentally friendly, avoiding toxic catalysts and focusing on scalability for industrial applicati…
Enantiopure quaternary amino acids, carrying two carbon-based substituents at the α carbon, are one of the most important groups of modified α amino acids, of great commercial value in the development of new pharmaceuticals and agrochemicals.
Certain of these quaternary amino acids are readily available by stereoselective α alkylation of available amino acids, but not those functionalized by the addition of α-aryl groups.
In this project, we propose to develop an industrially scalable, practical…
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