CORDIS Project
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This project addresses aging by analyzing large-scale human tissue imaging data to understand how cellular changes lead to age-related diseases. It aims to identify early predictors of pathology and redefine the relationship between aging and disease manifestation.
Aging is a complex biological process that manifests across diverse anatomical scales, from molecules and cells to organs and organisms.
Despite the significance of age-associated diseases in affecting quality of life and mortality, our understanding of how cellular-level changes result in tissue-specific loss of function remains incomplete.
Several limitations persist: the inability of animal models to fully mirror human physiology, the restricted scope of longitudinal human studies to easily a…
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