CORDIS Project
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This research project investigates the mechanisms regulating the degradation of nuclear pore complexes (NPCs) in yeast. By identifying the machinery and triggers involved in the formation of NPC-containing vesicles, the study aims to enhance understanding of NPC quality control and its implications for cellular functio…
The nucleus, surrounded by the nuclear envelope (NE), houses genetic material, and nuclear pore complexes (NPCs) mediate the selective passage of molecules between the nucleus and the cytoplasm. NPCs are critical for cellular functions such as protein synthesis and cell division.
Dysfunction of NPCs is associated with ageing and disease, highlighting the importance of quality control mechanisms such as NPC degradation.
However, the pathways that control NPC degradation remain largely uncharacter…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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