CORDIS Project
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The PyroPop project investigates programmed cell death mechanisms, particularly the role of inflammasomes in switching between different cell death modes. The goal is to understand how these processes can be manipulated for therapeutic benefits in inflammatory diseases.
Programmed cell death is essential for homeostasis, and its deregulation contributes to human disease.
Inflammasome-induced pyroptosis of infected macrophages contributes to host defense against infections, but the concomitant release of inflammatory danger signals and leaderless cytokines is detrimental in chronic inflammatory diseases.
The central hypothesis of the PyroPop ERC Consolidator project is that inflammasomes are cytosolic platforms that couple pathogen sensing to multiple programmed…
UNIVERSITEIT GENT
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VLAAMS INSTITUUT BIOTECHNOLOGIE FLANDERS INSTITUTE FOR BIOTECHNOLOGY
Belgium, ZWIJNAARDE - GENT
Type: Research institute
Activity type: Research Organisations
SME: No
Belgium, Beerse
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
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