CORDIS Project
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The project investigates the role of protein pyrophosphorylation, a recently discovered modification, in cellular processes. It aims to develop a method for site-specific pyrophosphorylation of proteins to study its biological significance and effects on protein interactions.
Post-translational modifications (PTMs) occur on nearly all proteins in eukaryotic cells to diversify their proteome.
These chemical modifications of various amino acids side chains can influence protein association with other biomolecules, or control cellular signal transduction networks and the activity of enzymes.
Reversible protein phosphorylation is one of the most common PTMs.
It is considered as a signalling mechanism involved in almost all cellular processes.
On the other hand, protein p…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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