CORDIS Project
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This project focuses on improving distance measurements in pulsed electron paramagnetic resonance (EPR) for structural studies of membrane proteins. It aims to address challenges related to data analysis in multi-spin systems, enhancing the accuracy of structural modeling in complex biological environments.
Pulse EPR distance measurements have evolved to a standard tool for generating long-range constraints for structural modelling via pulsed dipolar spectroscopy.
Especially the pulsed electron−electron double resonance (PELDOR or DEER) method is becoming increasingly applied.
The method is particularly promising for structural studies on different functional states of membrane proteins which are difficult to access by most biophysical methods.However, in samples of membrane proteins several approx…
THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS
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