CORDIS Project
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This project investigates the role of phenol soluble modulins (PSMs) in Staphylococcus aureus infections, focusing on how these peptides influence neutrophil behavior and immune evasion. By employing advanced imaging and molecular techniques, the research aims to clarify the mechanisms behind PSMs' dual functions in at…
Staphylococcus aureus community-acquired (CA)-MRSA strains are highly virulent and can cause infections in otherwise healthy individuals and are a leading cause of death worldwide.
Innate immunity is our primary defense against invading staphylococci.
Blood-neutrophils migrate to the site of infection where they, in concert with the complement system, engulf and kill bacteria in a process called phagocytosis.
Especially CA-MRSA strains seem to be very efficient in circumventing this neutrophil k…
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
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