CORDIS Project
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The PSMNano project investigates how phenol-soluble modulins α3 from Staphylococcus aureus interact with cell membranes, contributing to their harmful effects. By using advanced imaging techniques, the project aims to reveal the molecular mechanisms behind these interactions, which could lead to new therapeutic strateg…
Phenol-soluble modulins α3 (PSMα3) are functional amyloids involved in the virulence of Staphylococcus aureus, a multi-drug resistant pathogen under the surveillance of the European Union (EU).
The project PSMNano aims at unveiling the molecular mechanisms driving PSMα3 interactions with cell membranes, which lead to their cytotoxic and proinflammatory activities, with a focus on the impact of amyloid fibrillation.
So far poorly known, dissecting those mechanisms is yet critical to efficiently t…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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France, Bordeaux
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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