CORDIS Project
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This research focuses on the regulatory mechanisms of biofilm formation in bacteria, particularly Pseudomonas aeruginosa. It aims to investigate how extracellular polysaccharides signal within biofilms to enhance bacterial communication and resistance to treatments.
Many bacteria grow on a surface in communities called biofilms.
Cells growing in a biofilm are encapsulated by extracellular polymeric substances such as polysaccharides and proteins.
Bacterial biofilms are medically important as a number of chronic infections, such as cystic fibrosis (CF) airway infections, endocarditis, and periodontitis, are strongly associated with biofilm formation.
Biofilms cause pathological changes to infected tissues and are problematic due to their increased resistance…
UNIVERSITY OF BATH
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