CORDIS Project
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This project uses molecular dynamics simulations to explore how proteins communicate signals internally, focusing on G-protein coupled receptors and PDZ protein binding domains. By analyzing protein dynamics, the research aims to clarify the mechanisms of signal transduction, which could lead to new therapeutic strateg…
Signal transduction enables biological cells to respond to external stimuli such as light, odours, hormones, or growth factors.
Signalling is involved in numerous biological processes and dysfunction of signalling has been associated to severe conditions such as cancer or Alzheimer’s disease.
Whereas the knowledge of signal transduction on the cellular level has seen impressive progress within the last years, the molecular mechanisms involved in signalling remain mostly unknown.
Intra-protein si…
UPPSALA UNIVERSITET
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