CORDIS Project
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This project aims to investigate the role of extremely long-lived proteins in oocytes, which are crucial for female fertility. By analyzing protein turnover and modifications, it seeks to uncover mechanisms that maintain oocyte health and longevity, addressing gaps in reproductive biology.
Oocytes form during embryonic development and persist in a dormant state for decades, representing some of the longest-lived cells in our body.
As oocytes transfer their cytoplasm to the early embryo and the next generation, the regulation of its quality serves as a unique evolutionary strategy to preserve cellular longevity and fertility.
Protein turnover is essential for replacing damaged molecules with their functional copies since long lifespans expose proteins to damage accumulation, includ…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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