CORDIS Project
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This project investigates the inner nuclear membrane's role in cellular processes and disease. It aims to understand the mechanisms that maintain its integrity and identity, which are crucial for cell function.
The nuclear envelope (NE) is a major hub of eukaryotic cellular organization, influencing a myriad of processes, from gene regulation and repair to cell motility and fate.
This central role of the NE depends on its elaborate structure, particularly on the organization of its inner nuclear membrane (INM).
This peculiar membrane is continuous with the rest of the endoplasmic reticulum (ER) but faces the nucleoplasm and contains a distinctive set of proteins, which confer a unique identity to the I…
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