CORDIS Project
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This project aims to develop new synthetic molecules with dynamic structures that can change conformation. By introducing entanglements and photoswitchable elements, it seeks to create advanced materials with protein-like functions.
The most sophisticated functions of proteins emerge at the level of their tertiary structure and involve large amplitude conformational changes.
In contrast, the functions of synthetic molecules are currently limited by our inability to control their structure beyond the level of static secondary structures.
ProteoKnot seeks to address this limitation by introducing entanglements as a tool to control tertiary folding while maintaining the flexibility required to allow them to change conformation…
JYVASKYLAN YLIOPISTO
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