CORDIS Project
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This project investigates the connection between rheumatoid arthritis and periodontitis, focusing on how the bacterium Porphyromonas gingivalis may trigger autoimmune responses in genetically susceptible individuals. By analyzing genetic and immune factors, the project aims to uncover new pathways for potential therapi…
Autoimmunity in rheumatoid arthritis (RA) is characterised by an antibody response to citrullinated proteins.
Periodontitis (PD) is largely caused by infection, in whichPorphyromonas gingivalis is a major pathogen.
The two diseases combine specific HLA-DRB1alleles and smoking as risk factors, and have a similar pathophysiology characterised by destructive inflammation. A possible causative link between RA and PD is based on the ability of P. gingivalis to citrullinate proteins and thereby genera…
UNIVERSITETET I BERGEN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Poland, KRAKOW
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Sweden, Stockholm
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, PLANEGG MARTINSRIED
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
Denmark, Aarhus C
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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