CORDIS Project
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This project focuses on the defense mechanisms of bacteria against viral infections, using the bacterium Pseudomonas aeruginosa as a model. It aims to understand the ecological conditions that enhance the effectiveness of these defense systems, which has implications for medical treatments and industrial applications.
Bacteria and Archaea often experience invasions from selfish genetic elements, such as viruses.
These parasitic elements abuse host cells for multiplying and spread.
To defend themselves, prokaryotes developed a number of immune systems, such as Abortive Infection systems, Restriction/Modification systems and CRISPR/Cas.
Although the biochemistry of these immune systems has been studied in molecular detail over the last decade(s), much of their biological significance under ecologically relevant…
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