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The PROTECT project investigates the role of blood vessel types, particularly type R capillaries, in bone health and osteoporosis. It aims to understand how these endothelial cells contribute to bone formation and loss, with a focus on age and sex differences, to inform future therapies for osteoporosis.
During healthy aging but also in osteoporosis, a disease that affects more than 22% of European women beyond the age of 50, loss of mineralized bone is caused by a disbalance between bone formation and resorption.
While blood vessels are abundant in the skeletal system and play essential roles, they are currently not considered in the context of anti-osteoporosis therapy.
Moreover, apart from the role of sex hormones, we know too little about the impact of sex-specific regulators in physiologica…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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