CORDIS Project
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This project focuses on developing new small-molecule PROteolysis-TArgeting Chimerics (PROTACs) to degrade proteins involved in cancer progression. By targeting and degrading these proteins, the project aims to address drug resistance in cancer therapies, enhancing treatment efficacy while minimizing systemic exposure.
Cancer diseases are critical medical problems - according to the International Agency for Research on Cancer and European Commission estimates, globally there were more than 18 million new cases and 9.5 million cancer-related deaths in 2018, what indicates that tumors are among the leading causes of death, worldwide.
Traditional anticancer drug design based on small molecules continues to be a powerful strategy for the development of novel chemotherapeutics.
However, these anticancer therapies a…
FUNDACION UNIVERSITARIA SAN PABLO-CEU
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