CORDIS Project
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This project investigates how antibiotic resistance genes are transferred among bacteria via temperate bacteriophages. By studying the evolution of these prophages in E. coli, the research aims to understand the costs and benefits of carrying antibiotic resistance in different environments.
In the European Union, 25,000 deaths per year are caused by multidrug resistant bacteria.
This trend is predicted to increase with ever increasing misuse and overuse of antibiotics, which accelerates the evolution of antibiotic resistance (AR).
An important mechanism of transferring antibiotic resistance genes (ARGs) among bacteria are temperate bacteriophages (prophages), viruses that can incorporate their own genetic material into the bacterial chromosome, thereby providing their bacterial hos…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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