CORDIS Project
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The PROOF project aims to improve outcomes for ischemic stroke patients by using normobaric hyperoxygenation to increase oxygen supply to the brain's penumbra. This approach seeks to reduce brain injury and extend the treatment window for patients with salvageable tissue after a stroke.
Ischemic stroke (IS), caused by occlusion of arteries that supply blood to the brain, remains a leading cause of mortality and morbidity in the world.
Disruption of blood and oxygen supply to the brain leads to neuronal death in the ischemic core within minutes.
The hypoperfused tissue surrounding the ischemic core, the penumbra, is at high risk for infarction over time but still salvageable.
Neuroprotective “bridgingâ€, sustaining the penumbra until reperfusion, may widen the therapeutic win…
EBERHARD KARLS UNIVERSITAET TUEBINGEN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
UNIVERSITAETSKLINIKUM TUEBINGEN
Germany, TUEBINGEN
Type: Research institute
Activity type: Research Organisations
SME: No
Belgium, Leuven
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Czechia, Brno
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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