CORDIS Project
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This project explores the Notch signaling pathway's role in regulating cell growth and proliferation in Drosophila. By identifying key genes involved in this process, it aims to provide insights into how similar mechanisms may contribute to tumor development in humans.
During development the different organs and tissues of an organism have to grow harmoniously to reach their specific shapes and sizes.
In the adult, organs have usually reached an equilibrium, where loss of cells must be compensated by tightly regulated proliferation.
During cancer, groups of cells evade these controls and start to proliferate abnormally.The Notch intercellular signalling pathway is very conserved throughout evolution and directs a wide variety of cell fate decisions and behavio…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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