CORDIS Project
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This project develops a novel vaccine platform using protein nanocages to present immunogens from Gram-negative bacteria. By enhancing immune targeting and presentation, it aims to create effective vaccines against challenging bacterial infections.
Pathogenic bacteria pose significant threats to the global healthcare and the economy.
Amid growing concerns over antimicrobial resistance, many healthcare programs have pivoted to vaccine development, while new vaccine platforms are in a high demand for disease control and swift responses in the case of health emergencies. A major type of bacterial immunogen is transmembrane beta-barrel (TMB) proteins, which are found on the outer membrane of Gram-negative bacteria and play key roles in virulen…
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