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The ProMisMe project focuses on developing engineered bacteria and yeast to discover compounds that can correct the misfolding of membrane proteins associated with various diseases, including Usher Syndrome III and Charcot-Marie-Tooth disease. By utilizing ultrahigh-throughput screening of biosynthesized drug-like mole…
Protein misfolding diseases (PMDs) are a large group of human disorders caused by the misfolding of specific proteins.
They include conditions with high socio-economic impact, such as Alzheimer’s disease, cystic fibrosis, obesity and type 2 diabetes, and the majority of them remain incurable.
Among the >70 PMDs, about 1/3 are caused by misfolding-prone membrane proteins (MisMPs).
Despite their significance, and mainly due to the difficulties associated with MisMP overexpression, isolation and ch…
BIOMEDICALSCIENCES RESEARCH CENTER ALEXANDER FLEMING
EREVNITIKO KENTRO VIOIATRIKON EPISTIMON ALEXANDROS FLEMINGK
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RESQ BIOTECH IDIOTIKI KEFALAIOUCHIKI ETAIREIA
Greece, PATRA
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
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