CORDIS Project
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This project focuses on developing methods to convert ordinary cells into tissue-specific precursor cells to enhance tissue regeneration. By utilizing organoid technology, it aims to create a scalable system for testing reprogramming strategies to replenish stem cell populations for tissue repair.
In adult organisms, the natural ability to regenerate tissues damaged by injury or aging resides in multipotent tissue-specific precursors in local microenvironments.
The number of these precursors is often either limited or declines sharply with age.
Moreover, long-term adverse side effects of cancer treatments affect patients of any age.
Such treatments tend to diminish the stem cell and progenitor cell populations.In mammals pluripotency occurs only in the early embryo.
Since 2006 it has been…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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