CORDIS Project
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This project focuses on understanding the role of KAT2A, a histone acetyltransferase, in Acute Myeloid Leukaemia (AML). It aims to investigate how KAT2A influences cancer development through its effects on protein acetylation.
The importance of an insight into how cell fate is established and maintained, extends far beyond the interests of developmental biology.
It is pivotal to our understanding of how these processes can be hijacked and deranged in diseases such as cancer, or of the factors involved in reprogramming cell identity and function.
Acute Myeloid Leukaemia (AML) has a dismal prognosis with less than 30% 5-year survival.
Mainstay therapy has remained essentially unchanged for the past three decades, with a…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
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Guests see up to 5 EuroSciVoc fields.
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