CORDIS Project
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This project investigates the role of bile acids in regulating energy metabolism and glucose levels, targeting the NTCP transporter to enhance bile acid signaling. The goal is to develop new strategies to treat metabolic diseases like diabetes and atherosclerosis by modulating bile acid dynamics.
Bile acids play a pivotal role in energy supply as they facilitate the solubilization and absorption of fat in the intestine.
Furthermore, bile acids are recently identified as important signalling molecules regulating glucose metabolism, inflammation and energy expenditure.
Targeting bile acid signalling is, therefore, appealing to treat metabolic diseases such as diabetes and atherosclerosis.
These disorders are potentially affecting >1 billion individuals worldwide and current options to trea…
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
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