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ProLiCell explores the use of ultra-soft materials, including liquids, for cell culture, challenging traditional beliefs about solid substrates. The project focuses on engineering protein nanosheets that facilitate cell adhesion and proliferation, enabling innovative applications in stem cell technology and tissue engi…
A long standing dogma in the field of cell-based technologies is that bulk mechanical properties of solid substrates are essential to enable cell spreading, proliferation and fate decision.
The use of solid materials to culture adherent cells constitutes an important hurdle for the scale up, automation and speed up of cell culture and recovery.
Our recent results show that bulk solid substrates are not necessary to promote cell adhesion, growth and fate regulation as adherent stem cells spread a…
QUEEN MARY UNIVERSITY OF LONDON
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