CORDIS Project
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This project aims to create a compact super-resolution microscope integrated into a microfluidic chip to analyze chromatin organization in cancer cells. By enabling high-throughput imaging of individual cells, it seeks to enhance understanding of tumor heterogeneity and improve cancer treatment strategies.
Cancer is both a genetic and an epigenetic disease whose outcome is influenced by tumor microenvironment, which represents the major driving force of tumorigenesis causing the functional heterogeneity observed in most cancer types.
Defining the 3D-organization of cancer-associated chromatin domains would represent a new frontier to decipher tumor heterogeneity.
None of the currently available technologies permit to rapidly analyze thousands of cells and profile their chromatin organization at si…
CONSIGLIO NAZIONALE DELLE RICERCHE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Italy, Milano
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom, LONDON
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Italy, Trento
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
UNIVERSITE LYON 1 CLAUDE BERNARD
France, Villeurbanne Cedex
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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