CORDIS Project
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This project investigates cancer cell dynamics by analyzing protein expression at the single-cell level. It aims to understand the spatial and temporal heterogeneity of tumors to inform the development of personalized treatments for metastatic cancer, particularly in melanoma and breast cancer.
Cancer is an enormous biomedical challenge, in part due to the complexity of cancer cell dynamics.
The combination of intrinsic genetic alterations and cues from the tumour microenvironment impact the cancer phenotype and create heterogeneous tumours that evolve in space and time.
Cancer cells develop distinct phenotypes in diverse tumour regions and different metastatic locations.
In addition, cancer progression, metastatic dissemination, and development of therapeutic resistance affect cellula…
WEIZMANN INSTITUTE OF SCIENCE
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