CORDIS Project
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This project investigates the role of prenylation, a process that modifies proteins with lipid components, in immune response and inflammation. By creating genetically modified mice with specific deficiencies in prenylation-related enzymes, the project aims to understand how these modifications influence cell behavior…
Prenylation is a postranslational process leading to changes in protein structure due to the incorporation of a lipidic moiety that significantly modifies their physicochemical properties and their behaviour.
Prenylation is therefore a crucial step for key cell processes, such as interaction between proteins, cell and differentiation, cytoskeletal function and vesicular trafficking.
The modification of prenylation is proposed as an attractive option in biological and therapeutic research, as its…
UNIVERSITATSKLINIKUM ERLANGEN
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