CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the dual roles of B cells in immunity, focusing on their production of cytokines like interleukin-10 and interleukin-6. By characterizing these cells in mice, the aim is to identify markers that distinguish their pro-inflammatory and anti-inflammatory functions, which could inform new therapie…
B cells can act both as negative regulators and as drivers of immunity through the production of cytokines.
Through secretion of interleukin (IL)-10 B cells inhibited immunity in autoimmune and infectious diseases.
For instance, IL-10 from B cells drove complete recovery from disease in experimental autoimmune encephalomyelitis (EAE), the primary animal model for multiple sclerosis (MS), while a lack of IL-10 production by B cells resulted in a severe chronic EAE. B cells can also suppress immun…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
