CORDIS Project
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This project aims to identify genetic drivers of lung squamous cell carcinoma, focusing on the TNIK gene. By exploring its role in cancer progression and potential as a therapeutic target, the research seeks to develop new treatment strategies for this prevalent cancer type.
Lung squamous cell carcinoma (LSCC) represents one third of lung tumours; 550,000 cases are diagnosed annually worldwide (20% occur in Europe).
Treatment options for this cancer type are still scarce.
Identification of LSCC genetic drivers is thus an essential unmet need for developing novel therapies for this disease.In a stepwise multidisciplinary approach, we will determine if TNIK (Traf-2 and Nck-interacting kinase), a gene amplified in almost 40% of LSCC cases, constitutes a therapeutic tar…
THE UNIVERSITY OF MANCHESTER
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