CORDIS Project
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This project addresses the challenge of antibiotic resistance by studying bacterial persisters, which survive antibiotic treatment through metabolic shutdown. It aims to develop new methods to control these persisters and enhance the effectiveness of antibiotic therapies.
The abusive use of antibiotics has led to multidrug-resistant bacteria and the acute threat of a post-antibiotic era.
However, apart from resisters, there is a subgroup of bacteria called persisters that surviveby recalcitrance to antibiotic treatment.
Persisters are not resistant to antibiotics but simply survive by metabolic shutdown.
Upon withdrawal of antibiotics, these persisters resuscitate and regenerate the colony.
They are heavily involved in failure of antibiotic treatment and the deve…
ALBERT-LUDWIGS-UNIVERSITAET FREIBURG
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