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The POSAT project trains researchers to address chronic rejection in organ transplantation. It focuses on developing methods to reduce inflammation post-transplant and identifying biomarkers for personalized treatment.
Organ transplantation is the treatment of choice for many patients with end-stage diseases.
Waiting lists are lengthening but the supply of donor organs has not expanded to meet this demand.
Chronic rejection resulting in late loss of graft function now represents the greatest clinical challenge, with many patients rejoining the waiting list years after an initial transplant operation.
Indeed, as many as a third of patients joining the kidney transplant waiting list have already chronically reje…
UNIVERSITY OF NEWCASTLE UPON TYNE
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