CORDIS Project
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This project focuses on developing a new optical imaging technique to monitor membrane potential in living cells using second-harmonic generation microscopy with porphyrin-based dyes. It aims to enhance the understanding of neuronal function and other excitable cells in their natural environments.
Based on recently published work from Anderson’s group in Oxford, this proposal aims to develop a new technique for optical imaging of membrane potential in living cells using second-harmonic generation (SHG) microscopy with porphyrin-based dyes.
This technology should enable the function of neurons, and other excitable cells, to be monitored in real time, with high spatial resolution, in their native networks.
The objectives of this project include (1) the synthesis of new porphyrins that bind…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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