CORDIS Project
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This project investigates the role of inositol pyrophosphates and inorganic polyphosphate in cellular signaling. It aims to understand how these molecules influence processes such as apoptosis and stress responses by linking their synthesis and signaling functions.
Cellular regulation by soluble inositol phosphate messengers has yielded surprising knowledge that reaches well beyond the rigorously characterized regulation of Ca2+ release by inositol 1,4,5-trisphosphate (IP3), the best-known inositol phosphate.
Inositol pyrophosphates belong to the diverse family of inositol polyphosphate species that have a range of signaling functions.
The best-characterized inositol pyrophosphates are diphosphoinositol pentakisphosphate (IP7) and the bis-diphosphoinositol…
MEDICAL RESEARCH COUNCIL
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