CORDIS Project
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POLYBIOL aims to replicate the complex lubrication mechanisms found in natural cartilage by creating synthetic polymer structures. This innovative approach seeks to develop new materials that mimic the low-wear and lubricious properties of biological systems for potential use in industrial and clinical applications.
Lubrication in nature is based on water, but only functions due to the presence of a host of biomolecules.
In articular (e.g. hip) joints, it appears that the lubrication system is even more complex than previously believed, involving multiple gradients in structures and properties.
Gels and brushes appear to play an important role in biolubrication, while highly confined, highly hydrated charged polymers are key to the important mechanical properties of cartilage.
Components such as hyaluronic…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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