CORDIS Project
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This project explores how the chemistry of polymers affects the behavior of the pathogen Vibrio cholerae. By examining factors like charge and hydrophobicity, it aims to develop new polymers that can influence bacterial adhesion and virulence.
Here, we will identify how polymer chemistry and composition affects the microbiology of a model pathogen, Vibrio cholerae.
To this end, we will explore the chemical space that mediates bacterial adhesion because this bacteria activates complex signaling networks that regulate its physiology following binding to surfaces and hosts.Three main research objectives are:a) To identify what is the role of charge:
Electrostatic interactions are critical in the initial attachment of bacteria to hosts an…
THE UNIVERSITY OF BIRMINGHAM
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