CORDIS Project
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This research investigates how cellular networks adapt to the loss of essential proteins, focusing on the polarity network in yeast. The project aims to uncover the mechanisms behind evolutionary robustness in cellular functions through experimental evolution and advanced imaging techniques.
Cells are often viewed as intricate machines, in which specific proteins work together in a tightly coordinated fashion to give rise to cellular functions.
Surprisingly however, some proteins that are essential for core cellular functions in one species are absent in closely related species, while the core function itself is maintained.
How this robustness is achieved, while the underlying molecular networks dramatically diversify during evolution is currently not understood.
As a post-doc I sho…
TECHNISCHE UNIVERSITEIT DELFT
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