CORDIS Project
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This project explores how plants detect and respond to viral infections through a newly discovered pathway involving double-stranded RNA sensing. By examining the roles of specific enzymes and immune receptors, the research aims to enhance understanding of plant immunity and improve agricultural resilience against viru…
Elimination of foreign nucleic acids is key to host survival and reproduction.
Long double-stranded RNA (dsRNA) in the cytoplasm is used to distinguish viral from host genetic material, and several metazoan dsRNA receptors elicit innate immune responses upon binding to dsRNA.
Plants are thought to rely exclusively on RNA interference (RNAi) to eliminate RNA with double-stranded features.
Two DICER-LIKE (DCL) enzymes, DCL4 and DCL2, act redundantly to cleave dsRNA into small interfering RNAs that…
KOBENHAVNS UNIVERSITET
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