CORDIS Project
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This project explores the role of mRNA methylation in regulating gene expression in plants. It examines how methylation interacts with gene silencing mechanisms to influence the expression of important genes, particularly in the context of plant immunity.
Modifications to mRNA, collectively known as the epitranscriptome, comprise a neglected layer of gene regulation.
The most abundant internal modification of mRNA is methylation of adenosine (m6A).
The aim of this proposal is to explain a recently discovered interplay between mRNA methylation, gene silencing and gene expression in plants.
Specific expressed Arabidopsis genes contain transposons within them that bear localised silencing marks that include methylation of DNA and modifications to hi…
UNIVERSITY OF DUNDEE
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