CORDIS Project
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This project investigates the regulation of phosphatidylinositol-4-phosphate (PI4P) by the phosphatase Sac1, focusing on its role in lipid homeostasis and cellular functions. Using an auxin-inducible degradation system in zebrafish, the research aims to understand how Sac1 affects lipid distribution and intracellular s…
Lipids are essential components of cell membranes.
Every organelle membrane is constituted of a unique composition of different lipid species.
This distinctive lipid distribution along organelle membranes is important to maintain the identity and functions of the different organelles.
In this research project, I aim to understand how the lipid species phosphatidylinositol-4-phosphate (PI4P) is regulated and how this affects lipid homeostasis and cellular functioning.
The PI4P distribution is imp…
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