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PIGYVAX focuses on developing a vaccine for Porcine Epidemic Diarrhea Virus (PEDV) using a yeast-based delivery system. The project aims to enhance immunity in sows to protect piglets from this significant swine disease.
PIGYVAX aims to create pig vaccine candidates against PEDV, a pathogen of swine causing significant challenges to the swine industry globally.
This project will utilize yeast-based vaccine carrying nanoparticles of measles ribonucleoprotein (RNP) fused with PEDV spike protein (S1).
The multimerization of monomeric S1 antigen through RNP will increase immunogenicity due to better recognition of antigen presenting cells.
As the yeast delivery system has strong auto-adjuvant properties, the vaccin…
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