CORDIS Project
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The project PICO-NGS develops a highly sensitive and parallel method for measuring proteins, protein-protein interactions, and post-translational modifications in human cells. This innovative technology aims to enhance research in pharmaceuticals, biotechnology, and agricultural sciences by providing deeper insights in…
In a human cell there are about 20k protein coding genes (genome) that originate ~100k proteins (proteome).
Proteins are involved in complex networks of protein-protein interactions (PPIs) influenced by post-translational modifications (PTMs), the interactome of living cells (~800,000 entities).
The genome is mostly static throughout cell lifetime and can be sequenced today in <1h.
The proteome and interactome are changing with e.g., environment and health, and not yet fully known.
Today's metho…
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