CORDIS Project
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This project explores the integration of artificial metalloenzymes and photoredox catalysis to enhance chemical reactions. By anchoring a nickel catalyst within a protein, it aims to achieve precise control over catalytic reactivity, potentially enabling the synthesis of valuable pharmaceutical compounds.
Artificial metalloenzymes have recently emerged as powerful tools to address the ever-growing requirements of chemistry to become more efficient and sustainable.
This methodology involves anchoring a reactive transition metal catalyst within a protein to exploit the secondary coordination sphere created around the new active site, which can induce selectivity in reactions and improve turnover numbers.Concomitantly, photoredox and metallophotoredox catalysis, where a small quantity of a light sen…
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