CORDIS Project
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This project focuses on precision medicine by developing high-throughput tracking technology to analyze the behavior of the nematode C. elegans in response to genetic and chemical changes. The goal is to map gene-behavior associations and design effective combination therapies for complex diseases.
A central goal of precision medicine is to tailor treatments for individuals based on their genomic sequence.
However, many common diseases are associated with mutations in multiple genes and drugs often interact with multiple targets, making it difficult to go from genome sequence to drug selection.
Spontaneous locomotion in the nematode C. elegans provides a model to address fundamental questions about the mapping between chemical and genetic perturbation and complex phenotypes.
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