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The PhaSeAD project investigates the role of the c-Abl protein kinase in Alzheimer's disease, focusing on its interactions with liquid-liquid phase separation. The research aims to understand c-Abl's effects on neuronal function and cytoskeletal dynamics, potentially revealing new therapeutic targets.
Neurodegenerative diseases like Alzheimer's disease (AD) are a major global health concern, affecting millions and placing significant economic burdens on healthcare systems.
Despite advancements in understanding AD pathogenesis, effective treatments remain elusive.
PhaSeAD (Phase separation in Alzheimer's disease and Phase-separated c-Abl dynamics) aims to explore the role of the c-Abl protein kinase in AD pathogenesis, focusing on its interaction with liquid-liquid phase separation (LLPS).
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DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV
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