CORDIS Project
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This project investigates the genetic factors influencing individual responses to statin therapy for cardiovascular disease prevention. By analyzing genetic variations in a large clinical trial, it aims to personalize treatment and identify patients who may not benefit from statins.
Cardiovascular disease is the leading cause of death in industrialized countries.
The prevention of cardiovascular disease is critically dependent on lipid lowering therapy, which includes the 3-hydroxymethyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins).
Although statins are the most prescribed class of drugs worldwide, and therapy is generally associated with a reduction in risk for cardiovascular events by 20-30%, clinical response can be highly variable and adverse eff…
Leiden University Medical Center
ACADEMISCH ZIEKENHUIS LEIDEN
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United Kingdom, Glasgow
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Ireland, Cork
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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