CORDIS Project
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This project focuses on understanding how intracellular pathogens like Mycobacteria and Salmonella affect phagosome trafficking in host cells. By employing a systems biology approach, it aims to develop mathematical models to enhance the clearance of these pathogens by immune cells.
To address the question of how intracellular pathogens modulate phagosome trafficking in the host cell we propose to use a systems biology approach, using an iterative cycle of experimental data, model, new experimental data, improved model.
The ultimate aim of our project is to develop a mathematical model of mycobacteria and Salmonella infection of macrophages that can be applied to find new interventions that promote clearance of intracellular bacteria by phagocytic cells, and so boost innate…
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Leiden University Medical Center
Netherlands, Leiden
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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